Machu Picchu is well-known for its location on a mountain above a lush cloud forest. Explore Cuzco’s own ruins—Tambomachay, Puka Pukara, Qenko, and Sacsayhuamán—over the course of a leisurely half-day or travel to the remains of the Sacred Valley at Ollantaytambo, Tipón, or Psac to get a taste of what’s to come. Don’t miss the Museo Casa Concha in Cuzco, which has hundreds of objects that Hiram Bingham, the discoverer of Machu Picchu, took out of the site and only brought back to Peru from Yale University in 2011, a century after discovery. In order to balance the abundance of Incan heritage, take a stroll through the San Blas district’s maze-like streets or the frenetic San Pedro market. As dusk falls over the Plaza de Armas, sip a pisco sour from a balcony bar.

Peru’s astonishing biodiversity and waves of immigration come together in a rich and varied cuisine; serious foodies should devote considerable time to Cuzco’s array of restaurants serving traditional meals and fusion twists. Peru’s iconic ceviche dish of fresh fish flash-marinated in lime and chili is best enjoyed at lunch, with an ice-cold Cusqueña beer and handfuls of cancha (toasted corn). An Andean staple, cuy (guinea pig), is served whole-roasted, or on pizza for the squeamish. Papas a la Huancaína is a dish that takes some of the region’s hundreds of potato varieties and drenches them in a creamy chili sauce. Lomo saltado is the flagship dish of Chifa, a fusion of Peruvian and Chinese flavors.

The colorful traditional dress of the Quechua-speaking indigenous people of Cuzco, topped with bowler-style hats for the women and woolen chullos for the men, will quickly become a familiar sight for visitors. Quechua itself pre-dated the arrival of the Incas, and today’s indigenous culture is an amalgam of pre-Incan, Incan, and colonial influences. Traditional dance enlivens Catholic ritual, while apus (mountain spirits) and other nature deities coexist alongside Jesus Christ and the Virgin Mary. The coca leaf is a vital part of local culture, chewed as a mild narcotic or to mitigate the symptoms of altitude sickness, and has an important ceremonial role.

There is more to shopping in Cuzco than baby alpaca sweaters, knitted hats, and naughty ceramics. Fashionistas will love the impossibly hip Kuna, showcasing the work of young Peruvian designers. In San Blas, Irish expat Eibhlin Cassidy of Hilo creates one-of-a-kind items with a burlesque twist. Admire stunning designs in Peruvian silver at any number of boutique jewelers, or the canvases of contemporary Peruvian artists at Fractal Dragon. Písac’s sprawling market and the less-visited Sunday markets of Chinchero, both in the Sacred Valley, are great destinations for treasure hunters. Those short on time needn’t fear: A multitude of tiny markets spill out of the alleys and patios of historic Cuzco.

The rainy season stretches from November to February and can create difficult conditions for trekkers. Daytime temperatures hover around 70°F year-round but nights are chilly, plunging from 45°F through the rainy season to a low of 35°F in July. Cuzco is 11,155 feet above sea level: Try to eat lightly, and avoid alcohol and strenuous exercise for the first few days. Coca tea is an effective local cure for altitude sickness. The language is Spanish; the currency is the sol (plural, soles). Tipping is not standard outside of upscale restaurants (where 10% is customary), but is generally appreciated. Traditionally dressed women and children posing for photos do so for a small tip of a couple of soles. Be aware of pickpockets.